Anticorps Polyclonal de lapin anti-CXCL2

CXCL2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16325-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 16325-1-AP (same clone as 16325-1-PBS)

  Human lung tissue was subjected to SDS PAGE followed by western blot with 16325-1-AP (CXCL2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16325-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16325-1-PBS cible CXCL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CXCL2 Protéine recombinante Ag9410
• Nom complet: chemokine (C-X-C motif) ligand 2
• Masse moléculaire calculée: 107 aa, 11 kDa
• Poids moléculaire observé: 9 kDa
• Numéro d’acquisition GenBank: BC015753
• Symbole du gène: CXCL2
• Identification du gène (NCBI): 2920
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCL2, also known as macrophage inflammatory protein 2-alpha (MIP2-alpha), is a member of CXC chemokine family that binds to CXC chemokine receptor 2 (CXCR2). CXCL2 is mainly produced by macrophages, endothelial cells, epithelial cells and tumor cells. CXCL2 plays important roles in various biological progresses such as angiogenesis, inflammation, immune response and cancer biological behaviors. Under inflammatory conditions in CNS, microglia and astrocytes may secrete CXCL2 as well as other chemokines, which induces chemotaxis and infiltration of circulatory neutrophils. Indeed, previous studies suggest that CXCL2 is involved in Alzheimer disease, multiple sclerosis and brain ischemia.

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