Anticorps Recombinant de lapin anti-CXCL4/PF4

CXCL4/PF4 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243087F2

N° de cat : 85647-1-PBS

Synonymes

CXCL4, PF4, SCYB4, C X C motif chemokine 4, C-X-C motif chemokine 4

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Galerie de données de validation

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  WB analysis of mouse serum using 85647-1-RR (same clone as 85647-1-PBS)

  mouse serum was subjected to SDS PAGE followed by western blot with 85647-1-RR (CXCL4/PF4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85647-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human peripheral blood platelets using 85647-1-RR (same clone as 85647-1-PBS)

  human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 85647-1-RR (CXCL4/PF4 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85647-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 85647-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84647-1-RR against Human CXCL4/PF4 were performed. The affinity constant is 0.625 nM.

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Informations sur le produit

85647-1-PBS cible CXCL4/PF4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CXCL4/PF4 Protéine recombinante Eg2129
• Nom complet: platelet factor 4
• Masse moléculaire calculée: 11 kDa
• Poids moléculaire observé: 11 kDa
• Numéro d’acquisition GenBank: NM_002619.4
• Symbole du gène: PF4
• Identification du gène (NCBI): 5196
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation

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