Anticorps Polyclonal de lapin anti-LIX/CXCL5

LIX/CXCL5 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10809-1-PBS

Synonymes

CXCL5, C X C motif chemokine 5, C-X-C motif chemokine 5, CXCL 5, CXCL-5

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Galerie de données de validation

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  WB analysis using 10809-1-AP (same clone as 10809-1-PBS)

  Untreated, PMA treated A549 cells were subjected to SDS PAGE followed by western blot with 10809-1-AP (CXCL5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10809-1-PBS in a different storage buffer formulation.

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  IHC staining of human intrahepatic cholangiocarcinoma using 10809-1-AP (same clone as 10809-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 10809-1-AP (CXCL5 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10809-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10809-1-PBS cible LIX/CXCL5 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LIX/CXCL5 Protéine recombinante Ag1079
• Nom complet: chemokine (C-X-C motif) ligand 5
• Masse moléculaire calculée: 12 kDa
• Poids moléculaire observé: 10-12 kDa
• Numéro d’acquisition GenBank: BC008376
• Symbole du gène: CXCL5
• Identification du gène (NCBI): 6374
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Chemokines are a class of pro-inflammatory cytokines that can recruit and activate chemotactic cells. CXCL5 is a member of the chemokine family binding CXCR2, a G-protein coupled receptor. CXCL5 is a chemokine that promotes tumor formation by triggering the migration of immune cells to tumors and promotes immmuno-suppressive characteristics of the tumor microenvironment. CXCL5 can also promote tumor cell metastasis and recruit vascular endothelial cells for angiogenesis.

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