Anticorps Recombinant de lapin anti-CXCR2

CXCR2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242766G3

N° de cat : 98353-4-PBS

Synonymes

CD182, Cmkar2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98353-4-RR (same clone as 98353-4-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed. This data was developed using the same antibody clone with 98353-4-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98353-4-RR (same clone as 98353-4-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98353-4-PBS in a different storage buffer formulation.

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Informations sur le produit

98353-4-PBS cible CXCR2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CXCR2 Protéine recombinante Eg2228
• Nom complet: interleukin 8 receptor, beta
• Masse moléculaire calculée: 40 kDa
• Numéro d’acquisition GenBank: NM_009909.3
• Symbole du gène: Cxcr2
• Identification du gène (NCBI): 12765
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CXCR2, also named as CD182, Cmkar2, Gpcr16, or Il8rb, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

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