Anticorps Recombinant de lapin anti-CXCR2

CXCR2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242766G3

N° de cat : 98353-4-RR

Synonymes

CD182, Cmkar2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98353-4-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using 98353-4-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules médullaires de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98353-4-RR cible CXCR2 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CXCR2 Protéine recombinante Eg2228
• Nom complet: interleukin 8 receptor, beta
• Masse moléculaire calculée: 40 kDa
• Numéro d’acquisition GenBank: NM_009909.3
• Symbole du gène: Cxcr2
• Identification du gène (NCBI): 12765
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CXCR2, also named as CD182, Cmkar2, Gpcr16, or Il8rb, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.

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