Anticorps Recombinant de lapin anti-CXCR4/CD184

CXCR4/CD184 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

241956H2

N° de cat : PE-98233

Synonymes

241956H2

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Galerie de données de validation

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  FC experiment of mouse thymocytes using PE-98233

  1x10^6 mouse thymocytes were surface stained with FITC Plus Anti-Mouse CD4 (GK1.5) (FITC-65104, Clone: GK1.5), and 0.1 ug PE Anti-Mouse CXCR4/CD184 Rabbit RecAb (PE-98233, Clone: 241956H2) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse thymocytes using PE-98233

  1x10^6 mouse thymocytes were surface stained with 0.1 ug PE Anti-Mouse CXCR4/CD184 Rabbit RecAb (PE-98233, Clone: 241956H2) (red) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: thymocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-98233 cible CXCR4/CD184 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chemokine (C-X-C motif) receptor 4
• Masse moléculaire calculée: 40kDa
• Numéro d’acquisition GenBank: NM_009911.3
• Symbole du gène: Cxcr4
• Identification du gène (NCBI): 12767
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

C-X-C chemokine receptor type 4 (CXCR4, also known as CD184) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609).

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