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Anticorps Recombinant de lapin anti-CXCR5

CXCR5 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241777A10

N° de cat : 84639-2-PBS

Synonymes

CXCR 5, CXC R5, CD185, Burkitt lymphoma receptor 1, BLR1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CXCR5 Recombinant antibody (84639-2-RR)

    WB analysis using 84639-2-RR (same clone as 84639-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84639-2-RR (CXCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84639-2-PBS in a different storage buffer formulation.

Informations sur le produit

84639-2-PBS cible CXCR5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Peptide
Nom complet chemokine (C-X-C motif) receptor 5
Masse moléculaire calculée 372 aa, 42 kDa
Poids moléculaire observé33 kDa
Numéro d’acquisition GenBankBC110352
Symbole du gène CXCR5
Identification du gène (NCBI) 643
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Initially discovered in 1992 as Burkitt's lymphoma receptor 1, CXCR5 (chemokine receptor 5, also known as CD185) is a seven-transmembrane G protein-coupled receptor (GPCR) protein (PMID: 32994482). CXCR5 is essential for naïve B-cell migration to and maturation in the lymph nodes and spleen, as well as for cluster of differentiation 4 T-cell (TFH and TCM) homing and interaction with B cells (PMID: 21471443). Moreover, CXCR5 is involved in the regulation of neural stem cells (NSC) and neuronal regeneration in the mouse brain, neuronal differentiation, neurogenesis, gliogenesis, and synaptogenesis (PMID: 37460877).

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