Anticorps Recombinant de lapin anti-CXCR6

CXCR6 Recombinant Antibody for IF-P

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF-P

Conjugaison

APC Fluorescent Dye

CloneNo.

241662E5

N° de cat : APC-84591

Synonymes

CXCR 6, CXC R6, CDw186, CD186, BONZO

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Galerie de données de validation

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  IF Staining of human tonsillitis using APC-84591

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human tonsillitis tissue using APC CXCR6 antibody (APC-84591, Clone: 241662E5 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IF Staining of human tonsillitis using APC-84591

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human tonsillitis tissue using APC CXCR6 antibody (APC-84591, Clone: 241662E5 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en IF-P: tissu d'amygdalite humain,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-84591 cible CXCR6 dans les applications de IF-P et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: chemokine (C-X-C motif) receptor 6
• Masse moléculaire calculée: 39 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC033584
• Symbole du gène: CXCR6
• Identification du gène (NCBI): 10663
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul contiennent 0,1% de BSA.

Informations générales

CXCR6, or C-X-C chemokine receptor 6, is a G protein-coupled receptor with seven transmembrane domains that belong to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. CXCR6 is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signaling pathway that regulates T lymphocyte migration to various peripheral tissues such as the liver, spleen red pulp, intestine, lungs, and skin. CXCR6 plays a crucial role in immunosurveillance through its interaction with epithelial cells and certain subpopulations of intratumor dendritic cells (DC), particularly DC3, which express CXCL16 at the membrane.

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