Anticorps Polyclonal de lapin anti-CXCR7

• Phare
• Validé par KD/KO

CXCR7 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20423-1-PBS

Synonymes

ACKR3, CXC R7, C-X-C chemokine receptor type 7, CMKOR1, Chemokine orphan receptor 1

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Galerie de données de validation

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  WB analysis of Raji using 20423-1-AP (same clone as 20423-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 20423-1-AP (CXCR7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  WB analysis of K-562 using 20423-1-AP (same clone as 20423-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 20423-1-AP (CXCR7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 20423-1-AP (same clone as 20423-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 20423-1-AP (CXCR7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse thymus using 20423-1-AP (same clone as 20423-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 20423-1-AP (CXCR7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  IP experiment of HUVEC using 20423-1-AP (same clone as 20423-1-PBS)

  IP result of anti-CXCR7 (IP:20423-1-AP, 3ug; Detection:20423-1-AP 1:500) with HUVEC cells lysate 1400ug. This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20423-1-AP (CXCR7 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 20423-1-AP (same clone as 20423-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20423-1-AP (CXCR7 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20423-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20423-1-PBS cible CXCR7 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CXCR7 Protéine recombinante Ag14247
• Nom complet: chemokine (C-X-C motif) receptor 7
• Masse moléculaire calculée: 362 aa, 41 kDa
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: BC036661
• Symbole du gène: CXCR7
• Identification du gène (NCBI): 57007
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).

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