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Anticorps Recombinant de lapin anti-CXXC5

CXXC5 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241034A6

N° de cat : 83940-7-PBS

Synonymes

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CXXC5 Recombinant antibody (83940-7-RR)

    WB analysis using 83940-7-RR (same clone as 83940-7-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83940-7-RR (CXXC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83940-7-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83940-7-RR

    Affinity and Kinetic Characterization of 83940-7-RR

    Biolayer interferometry (BLl) kinetic assays of 83940-7-RR against Human CXXC5 were performed. The affinity constant is 5.73 nM.

Informations sur le produit

83940-7-PBS cible CXXC5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène CXXC5 Protéine recombinante Ag9733
Nom complet CXXC finger 5
Masse moléculaire calculée322aa,33 kDa; 227aa,24 kDa
Poids moléculaire observé 33-40 kDa
Numéro d’acquisition GenBankBC017439
Symbole du gène CXXC5
Identification du gène (NCBI) 51523
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812).

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