Anticorps Recombinant de lapin anti-CYP11B2

CYP11B2 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240811E7

N° de cat : 83930-1-PBS

Synonymes

240811E7, ALDOS, Aldosterone-synthesizing enzyme, Corticosterone 18-monooxygenase, CYP11B2, CPN2

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Galerie de données de validation

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  WB analysis of SKOV-3 using 83930-1-RR (same clone as 83930-1-PBS)

  SKOV-3 cells were subjected to SDS PAGE followed by western blot with 83930-1-RR (CYP11B2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83930-1-PBS in a different storage buffer formulation.

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Informations sur le produit

83930-1-PBS cible CYP11B2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: cytochrome P450, family 11, subfamily B, polypeptide 2
• Masse moléculaire calculée: 58 kDa
• Poids moléculaire observé: 58-60 kDa
• Numéro d’acquisition GenBank: NM_000498
• Symbole du gène: CYP11B2
• Identification du gène (NCBI): 1585
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).

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