Anticorps Recombinant de lapin anti-CYP24A1

CYP24A1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242142F2

N° de cat : 84821-3-PBS

Synonymes

CYP24, CP24, 24-OHase, 242142F2, 24 OHase

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Galerie de données de validation

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  WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84821-3-RR (CYP24A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84821-3-PBS in a different storage buffer formulation.

• 

  WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84821-3-RR (CYP24A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84821-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84821-3-PBS cible CYP24A1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CYP24A1 Protéine recombinante Ag17089
• Nom complet: cytochrome P450, family 24, subfamily A, polypeptide 1
• Masse moléculaire calculée: 514 aa, 59 kDa
• Poids moléculaire observé: 51 kDa
• Numéro d’acquisition GenBank: BC109083
• Symbole du gène: CYP24A1
• Identification du gène (NCBI): 1591
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CYP24A1(1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and 1-alpha,25-dihydroxyvitamin D3. Cholecalciferol is metabolized by the 25-hydroxylases (CYP2R1 and CYP27A1) in the liver before 25-hydroxycholecalciferol (25(OH)D3) relocates to the circulation (PMID:20362668). The gene CYP24A1 has three isoforms, for the transit peptide "mitochondrial domain" removed, the MW of CYP24A1 will be 55-59 kDa, 47-51 kDa, and 43 kDa. This antibody is specific to CYP24A1.

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