Anticorps Polyclonal de lapin anti-CYP2C8/9/18/19

CYP2C8/9/18/19 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16546-1-PBS

Synonymes

CP2C8, CYP2C8, CPC8, CYPIIC8, Cytochrome P450 2C8

---

Galerie de données de validation

• 

  WB analysis using 16546-1-AP (same clone as 16546-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16546-1-AP (CYP2C8/9/18/19 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16546-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 16546-1-AP (same clone as 16546-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 16546-1-AP (CYP2C8/9/18/19 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16546-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 16546-1-AP (same clone as 16546-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 16546-1-AP (CYP2C8/9/18/19 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16546-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

16546-1-PBS cible CYP2C8/9/18/19 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CYP2C8/9/18/19 Protéine recombinante Ag9898
• Nom complet: cytochrome P450, family 2, subfamily C, polypeptide 8
• Masse moléculaire calculée: 490 aa, 56 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC020596
• Symbole du gène: CYP2C8
• Identification du gène (NCBI): 1558
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CYP2C8(Cytochrome P450 2C8) is also named as CYPIIC8, cytochrome P450 IIC2, cytochrome P450 MP-12, cytochrome P450 MP-20, cytochrome P450 form 1 and S-mephenytoin 4-hydroxylase. It belongs to the cytochrome P450 family. It is a monooxygenase involved in an NADPH-dependent electron transport pathway and a hepatic drug-metabolizing enzymes that oxidizes therapeutic drugs such as cerivastatin and endobiotics such as retinoic acid and arachidonic acid. It has 2 isoforms produced by alternative splicing. This antibody can recognize human CYP2C 8/9/18/19, mouse CYP2C 29/37/38/39/55/65/, rat CYP2C6/7/11/12/13/23 due to the high homology.

{{ptg:RelatedPrimaryAntibodies}}