Anticorps Monoclonal anti-CYP2S1

CYP2S1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3E5D4

N° de cat : 68198-1-PBS

Synonymes

EC:5.3.99.5, EC:4.2.1.152, EC:1.14.14.-, Cytochrome P450 2S1, CYPIIS1

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Galerie de données de validation

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  WB analysis using 68198-1-Ig (same clone as 68198-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68198-1-Ig (CYP2S1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68198-1-PBS in a different storage buffer formulation.

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  WB analysis using 68198-1-Ig (same clone as 68198-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68198-1-Ig (CYP2S1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68198-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50889-4

  Cytometric bead array standard curve of MP50889-4, CYP2S1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68198-1-PBS. Detection antibody: 68198-6-PBS. Standard:Ag4605. Range: 0.391-100 ng/mL.

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Informations sur le produit

68198-1-PBS cible CYP2S1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CYP2S1 Protéine recombinante Ag4605
• Nom complet: cytochrome P450, family 2, subfamily S, polypeptide 1
• Masse moléculaire calculée: 504 aa, 56 kDa
• Poids moléculaire observé: 50-56 kDa
• Numéro d’acquisition GenBank: BC033691
• Symbole du gène: CYP2S1
• Identification du gène (NCBI): 29785
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The cytochrome P450 (CYP) family of isoenzymes are involved in the metabolism of diverse endogenous compounds and detoxification of exogenous agents. Cytochrome P450 2S1 (CYP2S1) is one 'orphan' CYP, and is particularly expressed in epithe-lial cells of tissues which are exposed to the environment such as the skin, respiratory, gastrointes-tinal, and urinary tracts. CYP2S1 is associated primarily with the synthesis and metabo-lism of lipids including prostaglandins (PGE2) and retinoids. In addition, CYP2S1 expression is associated with patient survival in breast cancer.

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