Anticorps Polyclonal de lapin anti-CYP4F8

CYP4F8 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20011-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 20011-1-AP (same clone as 20011-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20011-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20011-1-PBS cible CYP4F8 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: cytochrome P450, family 4, subfamily F, polypeptide 8
• Masse moléculaire calculée: 60 kDa
• Numéro d’acquisition GenBank: NM_007253
• Symbole du gène: CYP4F8
• Identification du gène (NCBI): 11283
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CYP4F8, also named as CPF8, belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. CYP4F8 hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. CYP4F8 shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. CYP4F8 catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). It catalyzes hydrxylation of PGI2 and carbaprostacyclin. The antibody has no cross reaction to other CYP4F member

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