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Anticorps Polyclonal de lapin anti-Cadherin-6

Cadherin-6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27703-1-PBS

Synonymes

CDH6, Cadherin 6, K cadherin, KCAD, K-cadherin

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using Cadherin-6 Polyclonal antibody (27703-1-AP)

    WB analysis using 27703-1-AP (same clone as 27703-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27703-1-AP (Cadherin-6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27703-1-PBS in a different storage buffer formulation.

Informations sur le produit

27703-1-PBS cible Cadherin-6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Cadherin-6 Protéine recombinante Ag26756
Nom complet cadherin 6, type 2, K-cadherin (fetal kidney)
Masse moléculaire calculée 790 aa, 88 kDa
Poids moléculaire observé130 kDa
Numéro d’acquisition GenBankBC000019
Symbole du gène Cadherin-6
Identification du gène (NCBI) 1004
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-6 (CDH6), also known as K-cadherin, is a class II cadherin involved in the morphogenesis of the central nervous system and kidney (PMID: 27375021). Expression of cadherin-6 has also been described in some cancers, including renal cancer, ovarian cancer, gastric cancer, and thyroid cancer (PMID: 14665853; 28526733; 34530820). Cadherin-6 is involved in epithelial-mesenchymal transition (EMT) and cancer metastasis (PMID: 27375021).

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