Anticorps Polyclonal de lapin anti-Calsequestrin 2

• Phare
• Validé par KD/KO

Calsequestrin 2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18422-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human heart using 18422-1-AP (same clone as 18422-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

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  WB analysis using 18422-1-AP (same clone as 18422-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 18422-1-AP (same clone as 18422-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 18422-1-AP (Calsequestrin 2 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 18422-1-AP (Calsequestrin 2 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skin using 18422-1-AP (same clone as 18422-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skin using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

• 

  IF Staining of C2C12 using 18422-1-AP (same clone as 18422-1-PBS)

  Immunofluorescent analysis of (-20℃ Ethanol) fixed C2C12 cell using 18422-1-AP (Calsequestrin 2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 18422-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18422-1-PBS cible Calsequestrin 2 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Calsequestrin 2 Protéine recombinante Ag13246
• Nom complet: calsequestrin 2 (cardiac muscle)
• Masse moléculaire calculée: 46 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC022288
• Symbole du gène: Calsequestrin 2
• Identification du gène (NCBI): 845
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Calsequestrin (CASQ) is a Ca2+-binding protein present primarily in junctional sarcoplasmic reticulum of skeletal and cardiac muscle; the cardiac form (CASQ2) is encoded by a separate gene. The primary role of CASQ2 is buffering of the sarcoplasmic reticulum Ca2+ ions, but another role for CASQ2 has emerged recently: CASQ2 regulates the open probability of ryanodine receptor 2 (RyR2). Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

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