Anticorps Recombinant de lapin anti-Cannabinoid receptor 1

Cannabinoid receptor 1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250285C8

N° de cat : 82787-2-PBS

Synonymes

CNR1, CANN6, cannabinoid receptor 1 (brain), CB R, CB1

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Galerie de données de validation

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  WB analysis of fetal human brain using 82787-2-RR (same clone as 82787-2-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 82787-2-RR (CNR1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82787-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82787-2-RR

  Biolayer interferometry (BLl) kinetic assays of 82787-2-RR against Human Cannabinoid receptor 1 were performed. The affinity constant is 22.3 nM.

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Informations sur le produit

82787-2-PBS cible Cannabinoid receptor 1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Cannabinoid receptor 1 Protéine recombinante Ag12625
• Nom complet: cannabinoid receptor 1 (brain)
• Masse moléculaire calculée: 472 aa, 53 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC074812
• Symbole du gène: Cannabinoid receptor 1
• Identification du gène (NCBI): 1268
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.

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