Anticorps Monoclonal anti-Caspase 2/P32/P18

Caspase 2/P32/P18 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2G4C2

N° de cat : 66517-1-PBS

Synonymes

CASP2, Caspase 2, 2G4C2, CASP 2, CASP-2

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Galerie de données de validation

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  WB analysis of Jurkat using 66517-1-Ig (same clone as 66517-1-PBS)

  Untreated and Staurosporine treated Jurkat cells were subjected to SDS PAGE followed by western blot with 66517-1-Ig (Caspase 2/P32/P18 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66517-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50435-1

  Cytometric bead array standard curve of MP50435-1, Caspase 2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66517-2-PBS. Detection antibody: 66517-1-PBS. Standard:Ag20141. Range: 0.098-25 ng/mL.

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Informations sur le produit

66517-1-PBS cible Caspase 2/P32/P18 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Caspase 2/P32/P18 Protéine recombinante Ag20141
• Nom complet: caspase 2, apoptosis-related cysteine peptidase
• Masse moléculaire calculée: 452 aa, 51 kDa
• Poids moléculaire observé: 48-51 kDa, 32 kDa, 18 kDa
• Numéro d’acquisition GenBank: BC002427
• Symbole du gène: Caspase 2
• Identification du gène (NCBI): 835
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

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