Anticorps Recombinant de lapin anti-CD38

CD38 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250107D11

N° de cat : 98433-3-PBS

Synonymes

ADP ribosyl cyclase/cyclic ADP ribose hydrolase, CD38 antigen, Cyclic ADP ribose hydrolase 1

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Galerie de données de validation

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  FC experiment of C57BL/6 mouse splenocytes using 98433-3-RR (same clone as 98433-3-PBS)

  1x10^6 C57BL/6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Cd38 Rabbit RecAb (98433-3-RR, Clone:250107D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 98433-3-PBS in a different storage buffer formulation.

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  FC experiment of C57BL/6 mouse splenocytes using 98433-3-RR (same clone as 98433-3-PBS)

  1x10^6 C57BL/6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Cd38 Rabbit RecAb (98433-3-RR, Clone: 250107D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98433-3-PBS in a different storage buffer formulation.

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Informations sur le produit

98433-3-PBS cible CD38 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD38 Protéine recombinante Eg2915
• Nom complet: CD38 antigen
• Masse moléculaire calculée: 34 kDa
• Numéro d’acquisition GenBank: NM_007646.5
• Symbole du gène: Cd38
• Identification du gène (NCBI): 12494
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

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