Anticorps Monoclonal anti-Clusterin

Clusterin Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2F12G10

N° de cat : 66109-1-PBS

Synonymes

Apo-J, APOJ, Apo J, Aging-associated gene 4 protein, AAG4

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Galerie de données de validation

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  WB analysis of human plasma using 66109-1-Ig (same clone as 66109-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66109-1-Ig (Clusterin antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 66109-1-Ig (same clone as 66109-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer slide using 66109-1-Ig (Clusterin antibody at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66109-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66109-1-PBS cible Clusterin dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Clusterin Protéine recombinante Ag19236
• Nom complet: clusterin
• Masse moléculaire calculée: 449 aa, 53 kDa
• Poids moléculaire observé: 36 kDa
• Numéro d’acquisition GenBank: BC010514
• Symbole du gène: CLU
• Identification du gène (NCBI): 1191
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).

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