Anticorps Monoclonal anti-COL6A2

COL6A2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3E9C2

N° de cat : 68652-1-PBS

Synonymes

3E9C2, Collagen alpha 2(VI) chain, Collagen alpha-2(VI) chain, Collagen Type VI

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Galerie de données de validation

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  WB analysis of human placenta using 68652-1-Ig (same clone as 68652-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 68652-1-Ig (COL6A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68652-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 68652-1-Ig (same clone as 68652-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 68652-1-Ig (COL6A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68652-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68652-1-PBS cible COL6A2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: COL6A2 Protéine recombinante Ag7134
• Nom complet: collagen, type VI, alpha 2
• Masse moléculaire calculée: 109 kDa
• Poids moléculaire observé: 140 kDa
• Numéro d’acquisition GenBank: BC065509
• Symbole du gène: COL6A2
• Identification du gène (NCBI): 1292
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Collagen VI, composed of three polypeptides, alpha-1(VI), alpha-2(VI), and alpha-3(VI) chains, is a beaded filament collagen found in most connective tissues. The alpha-1(VI) and alpha-2(VI) chains are 140 kDa, while the alpha-3(VI) chain is 200-300 kDa (PMID: 3792302, 3348212). COL6A2 gene encodes the alpha-2 subunit of type VI collagen. The alpha-2(VI) subunit has a calculated molecular weight of 109 kDa, and an apparent molecular weight of 140 kDa due to posttranslational modification. Mutations in COL6A2 gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

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