Anticorps Polyclonal de lapin anti-Collagen Type XI

Collagen Type XI Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21841-1-PBS

Synonymes

COL11, COL11A1, CO11A1, COLL6, Collagen alpha 1(XI) chain

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Galerie de données de validation

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  WB analysis using 21841-1-AP (same clone as 21841-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21841-1-AP (Collagen Type XI antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 21841-1-AP (same clone as 21841-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 21841-1-AP (Collagen Type XI antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 21841-1-AP (same clone as 21841-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 21841-1-AP (Collagen Type XI antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 21841-1-AP (same clone as 21841-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 21841-1-AP (Collagen Type XI antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 21841-1-AP (same clone as 21841-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 21841-1-AP (Collagen Type XI antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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  IF Staining of human placenta using 21841-1-AP (same clone as 21841-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human placenta tissue using Collagen Type XI antibody (21841-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21841-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21841-1-PBS cible Collagen Type XI dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Collagen Type XI Protéine recombinante Ag16509
• Nom complet: collagen, type XI, alpha 1
• Masse moléculaire calculée: 1818 aa, 182 kDa
• Poids moléculaire observé: 250 kDa, 181 kDa
• Numéro d’acquisition GenBank: BC117697
• Symbole du gène: COL11A1
• Identification du gène (NCBI): 1301
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

COL11A1 is an important component of collagen XI and is considered to play an important role in a variety of connective tissue diseases. Type XI collagen is widely distributed in tissues including cartilage, bone, and muscle, and its hereditary absence in Marshall's syndrome, Stickler's syndrome, fibrochondrogenesis, and nonsyndromic hearing loss deafness, autosomal dominant 37 leads to facial and eye abnormalities, hearing loss, and joint problems. The COL11A1 expression was significantly correlated with the degree of immune infiltration and the expression of a variety of immune cell markers in tumor tissue. (PMID: 36160004 33610546)

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