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Anticorps Recombinant de lapin anti-Complement factor D

Complement factor D Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242744B4

N° de cat : 85643-4-PBS

Synonymes

28 kDa adipocyte protein, Adipsin, Adn, C3 convertase activator, Cfd

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using Complement factor D Recombinant antibody (85643-4-RR)

    WB analysis using 85643-4-RR (same clone as 85643-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85643-4-RR (Cfd antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85643-4-PBS in a different storage buffer formulation.

Informations sur le produit

85643-4-PBS cible Complement factor D dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet complement factor D (adipsin)
Masse moléculaire calculée28 kDa
Poids moléculaire observé40-50 kDa
Numéro d’acquisition GenBankNM_013459.4
Symbole du gène Cfd
Identification du gène (NCBI) 11537
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Complement factor D, also known as adipsin, is a highly specific serine protease. Complement factor D is the rate-limiting enzyme in the alternative pathway of complement. It activates C3 convertase by cleaving factor B, which is a key step in the alternative pathway. Complement factor D catalyzes the cleavage of factor B to generate Ba (non-catalytic chain) and Bb (active catalytic subunit), which together with C3(H2O) (or C3b) constitute the active C3 convertase C3(H2O)Bb (or C3bBb). (PMID: 34566967; PMID: 27775713).

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