• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anticorps Recombinant de lapin anti-Complement factor H

Complement factor H Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242740E8

N° de cat : 85132-2-PBS

Synonymes

CFH, ARMD4, ARMS1, Factor H, FH

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of human plasma using Complement factor H Recombinant antibody (85132-2-RR)

    WB analysis of human plasma using 85132-2-RR (same clone as 85132-2-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 85132-2-RR (Complement factor H/CFH antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85132-2-PBS in a different storage buffer formulation.

Informations sur le produit

85132-2-PBS cible Complement factor H dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Complement factor H Protéine recombinante Eg3753
Nom complet complement factor H
Masse moléculaire calculée139kDa
Poids moléculaire observé140-150 kDa
Symbole du gène Complement factor H
Identification du gène (NCBI) 3075
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Complement factor H (CFH) is an abundant plasma glycoprotein that regulates the function of the alternative complement pathway in the fluid phase and on cellular surfaces (PMID: 2963625). Factor H binds to C3b, accelerates the decay of the alternative pathway C3-convertase (C3bBb), and acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b (PMID: 15163532). It plays a critical role in the homeostasis of the complement system in plasma and in the protection of bystander host cells and tissues from damage by complement activation. Abnormalities in factor H have been associated with renal disease (PMID: 18190458).

{{ptg:RelatedPrimaryAntibodies}}