Anticorps Polyclonal de lapin anti-Connexin 45

• Phare
• Validé par KD/KO

Connexin 45 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22184-1-PBS

Synonymes

Connexin-45, Cx45, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7

---

Galerie de données de validation

• 

  WB analysis using 22184-1-AP (same clone as 22184-1-PBS)

  mouse heart tissue was subjected to SDS PAGE followed by western blot with 22184-1-AP (Connexin 45 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 22184-1-AP (same clone as 22184-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 22184-1-AP (Connexin 45 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

22184-1-PBS cible Connexin 45 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Connexin 45 Protéine recombinante Ag16742
• Nom complet: gap junction protein, gamma 1, 45kDa
• Masse moléculaire calculée: 396 aa, 45 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC096213
• Symbole du gène: Connexin-45
• Identification du gène (NCBI): 10052
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Connexin 45 (Cx45), also known as Gap junction gamma protein (GJC1), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. A loss-of-function mutation in Cx45 contributing to Atrial fibrillation (AF) and other cardiac arrhythmias (PMID: 33429106).

{{ptg:RelatedPrimaryAntibodies}}