Anticorps Polyclonal de lapin anti-Connexin-50

Connexin-50 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23161-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 23161-1-AP (same clone as 23161-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23161-1-AP (Connexin-50 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23161-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23161-1-PBS cible Connexin-50 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Connexin-50 Protéine recombinante Ag19572
• Nom complet: gap junction protein, alpha 8, 50kDa
• Masse moléculaire calculée: 433 aa, 48 kDa
• Poids moléculaire observé: 60-65 kDa
• Numéro d’acquisition GenBank: BC146507
• Symbole du gène: GJA8
• Identification du gène (NCBI): 2703
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Connexin-50 (Cx50), also known as Gap junction alpha 8 protein (GJA8), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. Connexin-50 is expressed in lens fiber cells and is essential for the normal physiological function of the lens (PMID: 11916859). Together with Connexin-46, Connexin-50 forms functional half-gap junction channels in non-junctional membranes. The expected molecular weight of Connexin-50 is 50 kDa, and in some literature, Connexin-50 was detected in lens samples at ~65 kDa (PMID: 31195409; PMID: 29196765).

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