Anticorps Recombinant de lapin anti-Cryptochrome 2

Cryptochrome 2 Recombinant Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250166A8

N° de cat : 85866-1-PBS

Synonymes

CRY 2, CRY2, Cryptochrome-2, HCRY2, PHLL2

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Galerie de données de validation

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  WB analysis using 85866-1-RR (same clone as 85866-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85866-1-RR (Cryptochrome 2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85866-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 85866-1-RR (same clone as 85866-1-PBS)

  IP result of anti-Cryptochrome 2 (IP:85866-1-RR, 4ug; Detection:85866-1-RR 1:2000) with mouse brain tissue lysate 1720 ug. This data was developed using the same antibody clone with 85866-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85866-1-PBS cible Cryptochrome 2 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Cryptochrome 2 Protéine recombinante Ag38484
• Nom complet: cryptochrome 2 (photolyase-like)
• Masse moléculaire calculée: 593 aa, 67 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC041814
• Symbole du gène: CRY2
• Identification du gène (NCBI): 1408
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cryptochrome circadian clock 2 (CRY2) is a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. Loss of CRY2 stabilizes c-MYC and enhances cellular transformation. CRY2 can function as a co-factor for the SCF substrate adaptor FBXL3 (PMID: 27840026).

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