Anticorps Recombinant de lapin anti-CXCL1

CXCL1 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

240268D2

N° de cat : 98047-1-PBS

Synonymes

Growth-regulated alpha protein, chemokine (C X C motif) ligand 1, 240268D2

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98047-1-RR (same clone as 98047-1-PBS)

  1x10^6 untreated or LPS and Brefeldin A treated mouse splenocytes were intracellularly stained with 0.125 ug Anti-Mouse CXCL1 Rabbit Recombinant Antibody. Cells were then stained with APC Anti-Mouse TNFα. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98047-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98047-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98047-1-RR against Mouse CXCL1 were performed. The affinity constant is 35.4 nM.

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Informations sur le produit

98047-1-PBS cible CXCL1 dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chemokine (C-X-C motif) ligand 1
• Masse moléculaire calculée: 10kd
• Numéro d’acquisition GenBank: NM_008176
• Symbole du gène: Cxcl1
• Identification du gène (NCBI): 14825
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CXCL1 a is a member of CXC family and also known as keratinocyte-derived chemokines (KC) or growth-related oncogene (GRO). CXCL1 is expressed by macrophages, neutrophils and epithelial cells. CXCL1 binding specifically to the CXC chemokine receptor CXCR2, is involved in fibrogenesis and angiogenesis. This protein also plays a role in inflammation and as a chemoattractant for neutrophils. CXCL1 is upregulated in some types of human cancer, including colorectal, bladder, breast, prostate and skin cancers.

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