Anticorps Recombinant de lapin anti-CXCL13/BCA1

CXCL13/BCA1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250336E12

N° de cat : 86564-1-PBS

Synonymes

Cxcl13, B lymphocyte chemoattractant, BCA1, Blc, CXC chemokine BLC

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Galerie de données de validation

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  WB analysis using 86564-1-RR (same clone as 86564-1-PBS)

  Non-transfected and Cxcl13-transfected HEK-293T cell lysates were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at a dilution of 1:5000, incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86564-1-PBS in a different storage buffer formulation.

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  WB analysis of Recombinant protein using 86564-1-RR (same clone as 86564-1-PBS)

  Mouse Cxcl13 Recombinant protein (cat no. Eg4484) were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86564-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86564-1-PBS cible CXCL13/BCA1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CXCL13/BCA1 Protéine recombinante Eg3331
• Nom complet: chemokine (C-X-C motif) ligand 13
• Masse moléculaire calculée: 12 kDa
• Numéro d’acquisition GenBank: NM_018866
• Symbole du gène: Cxcl13
• Identification du gène (NCBI): 55985
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CXCL13 (C-X-C motif chemokine 13), originally named B-lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a homeostatic chemokine that is constitutively secreted by stromal cells in the B-cell follicles of secondary lymphoid tissues (e.g., spleen, lymph nodes, tonsils, and Peyer's patches). It plays a crucial role in orchestrating cell migration within distinct regions of secondary lymphoid organs, strongly attracting B lymphocytes (and, to a lesser extent, T cells and macrophages) via its receptor CXCR5 (originally named Burkitt's lymphoma receptor 1, BLR1). In addition to maintaining immune cell trafficking and lymphoid follicle development, CXCL13 is implicated in inflammatory and autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis) and tumor progression (e.g., multiple myeloma).

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