Anticorps Monoclonal anti-Cyclin D2

Cyclin D2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A12A8

N° de cat : 67048-1-PBS

Synonymes

CCND2, cyclin D, cyclin D2, G1/S specific cyclin D2, KIAK0002

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Galerie de données de validation

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  WB analysis using 67048-1-Ig (same clone as 67048-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67048-1-Ig (CCND2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67048-1-PBS in a different storage buffer formulation.

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  WB analysis of NIH/3T3 using 67048-1-Ig (same clone as 67048-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67048-1-Ig (CCND2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67048-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67048-1-PBS cible Cyclin D2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Cyclin D2 Protéine recombinante Ag25190
• Nom complet: cyclin D2
• Masse moléculaire calculée: 32 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC010958
• Symbole du gène: Cyclin D2
• Identification du gène (NCBI): 894
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.

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