Anticorps Recombinant de lapin anti-Cyclophilin E

Cyclophilin E Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250296A6

N° de cat : 85952-1-PBS

Synonymes

PPIE, Cyclophilin 33, Cyclophilin-33, CYP 33, CYP33

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Galerie de données de validation

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  WB analysis using 85952-1-RR (same clone as 85952-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85952-1-RR (Cyclophilin E antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85952-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85952-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85952-1-RR against Human Cyclophilin E were performed. The affinity constant is 58.2 nM.

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Informations sur le produit

85952-1-PBS cible Cyclophilin E dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Cyclophilin E Protéine recombinante Ag7603
• Nom complet: peptidylprolyl isomerase E (cyclophilin E)
• Masse moléculaire calculée: 33 kDa
• Poids moléculaire observé: 33 kDa
• Numéro d’acquisition GenBank: BC004898
• Symbole du gène: Cyclophilin E
• Identification du gène (NCBI): 10450
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cyclophilin E (CypE), also known as Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily (PMID: 15998457). Cyclophilin E negatively regulates influenza virus replication and transcription occurs by impairing the formation of the vRNP (PMID: 21887220). Additionally, Cyclophilin E plays an important role in osteoblast differentiation as a positive regulator by increasing the transcriptional activity of Runx2 (PMID: 37947627).

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