Anticorps Polyclonal de lapin anti-Cystatin S

Cystatin S Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26979-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human saliva using 26979-1-AP (same clone as 26979-1-PBS)

  human saliva were subjected to SDS PAGE followed by western blot with 26979-1-AP (Cystatin S antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26979-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26979-1-AP (same clone as 26979-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26979-1-AP (Cystatin S antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26979-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26979-1-AP (same clone as 26979-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26979-1-AP (Cystatin S antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26979-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26979-1-PBS cible Cystatin S dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Cystatin S Protéine recombinante Ag25619
• Nom complet: cystatin S
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: BC065714
• Symbole du gène: Cystatin S
• Identification du gène (NCBI): 1472
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cystatins are a family of inhibitors of cysteine peptidases that comprises the salivary cystatins D and S-type (including CST5 and CST4,1,2) and cystatin C-type (CST3) (PMID: 25329717). The D and S-type cystatin have also been detected in seminal plasma, tears, and tracheobronchial fluid but not in other fluids and secretions where cystatin C is found. And the CST4 was expressed in the serous acinar and demilune cells of the human submandibular gland and at lower levels in the serous acini of the parotid gland (PMID:11879580). CST4 specifically combines with cysteine protease to regulate its activity, thus preventing hydrolysis of the extracellular matrix. And some studies propose that CST4 might be a biomarker for gastrointestinal cancer (PMID:29218251; PMID:29636621).

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