Anticorps Polyclonal de lapin anti-DAZ

DAZ Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14065-1-PBS

Synonymes

DAZ4, DAZ 4, DAZ1, pDP1680, pDP1681

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Galerie de données de validation

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  WB analysis of human testis using 14065-1-AP (same clone as 14065-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 14065-1-AP (DAZ4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14065-1-PBS in a different storage buffer formulation.

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  WB analysis of rat testis using 14065-1-AP (same clone as 14065-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 14065-1-AP (DAZ4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14065-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14065-1-PBS cible DAZ dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DAZ Protéine recombinante Ag5116
• Nom complet: deleted in azoospermia 4
• Masse moléculaire calculée: 65 kDa
• Poids moléculaire observé: 60-65 kDa
• Numéro d’acquisition GenBank: BC047617
• Symbole du gène: DAZ4
• Identification du gène (NCBI): 57135
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DAZ4, encoded by the DAZ gene, is an RNA-binding protein with a role in spermatogenesis. DAZ4 is a testis-specific protein that expression restricted to premeiotic germ cells, particularly in spermatogonia. Defects in DAZ4 may be a cause of spermatogenic failure Y-linked type 2 (SPGFY2). It is a disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility.

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