Anticorps Polyclonal de lapin anti-DAZAP2

DAZAP2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15210-1-PBS

Synonymes

PRTB, Proline-rich transcript in brain protein, KIAA0058, Deleted in azoospermia-associated protein 2, DAZ-associated protein 2

---

Galerie de données de validation

• 

  WB analysis using 15210-1-AP (same clone as 15210-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15210-1-AP (DAZAP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15210-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

15210-1-PBS cible DAZAP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DAZAP2 Protéine recombinante Ag7364
• Nom complet: DAZ associated protein 2
• Masse moléculaire calculée: 17 kDa
• Poids moléculaire observé: 17 kDa, 22 kDa
• Numéro d’acquisition GenBank: BC002334
• Symbole du gène: DAZAP2
• Identification du gène (NCBI): 9802
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DAZAP2, also named KIAA0058, has six isoforms. In unstressed cells, it promotes SIAH1-mediated polyubiquitination and degradation of the serine/threonine-protein kinase HIPK2, probably by acting as a loading factor that potentiates complex formation between HIPK2 and ubiquitin ligase SIAH1. In response to DNA damage, it localizes to the nucleus following phosphorylation by HIPK2 and modulates the expression of a subset of TP53/p53 target genes by binding to TP53 at target gene promoters (PMID: 33591310).

{{ptg:RelatedPrimaryAntibodies}}