Anticorps Recombinant de lapin anti-DC-SIGNR/CD299

DC-SIGNR/CD299 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241683G8

N° de cat : 98205-1-RR

Synonymes

CLEC4M, CD299, CD209L1, CD209L, CD209 antigen-like protein 1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98205-1-RR

  1x10^6 HEK-293T cells or DC-SIGNR/CD299 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human DC-SIGNR/CD299 Rabbit Recombinant Antibody (98205-1-RR, Clone: 241683G8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using 98205-1-RR

  1x10^6 HEK-293T cells or DC-SIGNR/CD299 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human DC-SIGNR/CD299 Rabbit Recombinant Antibody (98205-1-RR, Clone:241683G8) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98205-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98205-1-RR against Human DC-SIGNR/CD299 were performed. The affinity constant is 3.68 nM.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98205-1-RR cible DC-SIGNR/CD299 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: C-type lectin domain family 4, member M
• Masse moléculaire calculée: 45 kDa
• Numéro d’acquisition GenBank: BC038851
• Symbole du gène: DC-SIGNR/CD299
• Identification du gène (NCBI): 10332
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Dendritic cell-specific intracellular adhesion molecule-3-grabbing non-integrin (DC-SIGN/CD209) and DC-SIGN related (DC-SIGNR/CD299/L-SIGN/CD209L/CLEC4M) are trans-membrane C-type lectins that are calcium-dependent carbohydrate-binding proteins, which can act as cell-adhesion and pathogen-recognition receptors (PMID: 18458800). DC-SIGN and DC-SIGNR share 77% amino acid identity (PMID: 10975799; 11226297). DC-SIGN is expressed on subsets of dendritic cells and macrophages while DC-SIGNR is restricted to endothelial cells of the liver, lymph nodes and placenta (PMID: 17509452). DC-SIGNR servers as a receptor for ICAM-3. It recognizes a wide range of evolutionarily divergent pathogens.

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