Anticorps Recombinant de lapin anti-DC-SIGNR/CD299

DC-SIGNR/CD299 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

241683G8

N° de cat : Biotin-FcA98205

Synonymes

CLEC4M, CD209 antigen like protein 1, CD209 antigen-like protein 1, CD209L, CD209L1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using Biotin-FcA98205

  1x10^6 untransfected (left) or CD299-transfected HEK-293T (right) cells were surface stained with 0.25 ug Biotin Anti-Human DC-SIGNR/CD299 Rabbit RecAb (Biotin-FcA98205, Clone: 241683G8) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE Streptavidin (Cat.No. PF00021). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using Biotin-FcA98205

  1x10^6 untransfected (left) or CD299-transfected HEK-293T (right) cells were surface stained with 0.25 ug Biotin Anti-Human DC-SIGNR/CD299 Rabbit RecAb (Biotin-FcA98205, Clone: 241683G8) (red) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9) (blue), and PE Streptavidin (Cat.No. PF00021). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-FcA98205 cible DC-SIGNR/CD299 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: C-type lectin domain family 4, member M
• Masse moléculaire calculée: 45 kDa
• Numéro d’acquisition GenBank: BC038851
• Symbole du gène: DC-SIGNR/CD299
• Identification du gène (NCBI): 10332
• Conjugaison: Biotin
• Excitation/Emission maxima wavelengths: -
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Dendritic cell-specific intracellular adhesion molecule-3-grabbing non-integrin (DC-SIGN/CD209) and DC-SIGN related (DC-SIGNR/CD299/L-SIGN/CD209L/CLEC4M) are trans-membrane C-type lectins that are calcium-dependent carbohydrate-binding proteins, which can act as cell-adhesion and pathogen-recognition receptors (PMID: 18458800). DC-SIGN and DC-SIGNR share 77% amino acid identity (PMID: 10975799; 11226297). DC-SIGN is expressed on subsets of dendritic cells and macrophages while DC-SIGNR is restricted to endothelial cells of the liver, lymph nodes and placenta (PMID: 17509452). DC-SIGNR servers as a receptor for ICAM-3. It recognizes a wide range of evolutionarily divergent pathogens.

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