Anticorps Polyclonal de lapin anti-DCDC2

• Phare
• Validé par KD/KO

DCDC2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 26978-1-PBS

Synonymes

DCDC2A, Doublecortin domain-containing protein 2, Protein RU2S, RU2, RU2S

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Galerie de données de validation

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  WB analysis of mouse placenta using 26978-1-AP (same clone as 26978-1-PBS)

  mouse placenta tissue were subjected to SDS PAGE followed by western blot with 26978-1-AP (DCDC2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26978-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 26978-1-AP (same clone as 26978-1-PBS)

  WB result of DCDC2 antibody (26978-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-DCDC2 transfected HepG2 cells. This data was developed using the same antibody clone with 26978-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26978-1-PBS cible DCDC2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DCDC2 Protéine recombinante Ag25577
• Nom complet: doublecortin domain containing 2
• Masse moléculaire calculée: 476 aa, 53 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC050704
• Symbole du gène: DCDC2
• Identification du gène (NCBI): 51473
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DCDC2 (Doublecortin domain-containing protein 2), also known as KIAA1154. DCDC2 is expressed in the central nervous system of adults and fetuses, especially in the olfactory cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. DCDCDC2 protein contains two dicortical protein domains that bind to microtubules and enhance microtubule polymerization, which may play a role in neuronal migration and affect the signal transduction of primary cilia. In addition, DCDC2 also plays a role in inhibiting classical WNT signaling. DCDC2 may affect the development and function of the brain by affecting the migration of neurons and the signal conduction of primary cilia, and then it is related to reading ability (PMID: 21457949). The molecular weight of DCDC2 is 52 kDa, it also has another isoform with a molecular weight of 25 kDa.

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