Anticorps Recombinant de lapin anti-DDR1/CD167a

DDR1/CD167a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241796D6

N° de cat : 98200-1-PBS

Synonymes

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

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Galerie de données de validation

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  FC experiment of MCF-7 using 98200-1-RR (same clone as 98200-1-PBS)

  1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 0.25 ug Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR, Clone: 241796D6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98200-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98200-1-PBS cible DDR1/CD167a dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: discoidin domain receptor tyrosine kinase 1
• Masse moléculaire calculée: 101 kDa
• Numéro d’acquisition GenBank: NM_001297654
• Symbole du gène: DDR1
• Identification du gène (NCBI): 780
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.

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