Anticorps Recombinant de lapin anti-DDR1/CD167a

DDR1/CD167a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241796D6

N° de cat : CL647-98200

Synonymes

DDR1, 241796D6, CAK, CD167, CD167 antigen-like family member A

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Galerie de données de validation

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  FC experiment of MCF-7 using CL647-98200

  1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 5 ul CoraLite® Plus 647 Anti-Human DDR1/CD167a Rabbit RecAb (CL647-98200, Clone: 241796D6) (red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules MCF-7,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98200 cible DDR1/CD167a dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: DDR1/CD167a Protéine recombinante Eg1675
• Nom complet: discoidin domain receptor tyrosine kinase 1
• Masse moléculaire calculée: 101 kDa
• Numéro d’acquisition GenBank: NM_001297654
• Symbole du gène: DDR1
• Identification du gène (NCBI): 780
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.

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