Anticorps Polyclonal de lapin anti-DDX11

DDX11 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13047-1-PBS

Synonymes

ATP-dependent DNA helicase DDX11, CHL1-related protein 1, DDX 11, DEAD/H-box protein 11, EC:3.6.4.12

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Galerie de données de validation

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  WB analysis using 13047-1-AP (same clone as 13047-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13047-1-AP (DDX11 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13047-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13047-1-PBS cible DDX11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DDX11 Protéine recombinante Ag3666
• Nom complet: DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)
• Masse moléculaire calculée: 970 aa, 108 kDa
• Poids moléculaire observé: 102-108 kDa
• Numéro d’acquisition GenBank: BC011264
• Symbole du gène: DDX11
• Identification du gène (NCBI): 1663
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DDX11 (DEAD/H-box helicase 11), also known as hCHLR1, KRG-2, is a member of the DExD/H (Asp-Glu-x-Asp/His)-box helicase family containing DNA helicase with roles in DNA replication and sister chromatid cohesion establishment, and general chromosome architecture (PMID: 33802088). DDX11 encodes an iron-sulfur cluster DNA helicase required for development, mutated, and overexpressed in cancers (PMID: 33879618). DDX11 is also a positive regulator of the RIG-I-mitochondrial antiviral signaling protein (MAVS)-mediated signaling pathways (PMID: 39470258).

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