Anticorps Polyclonal de lapin anti-DENND4A

DENND4A Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 26659-1-PBS

Synonymes

MYCPBP, KIAA0476, IRLB, DENN/MADD domain containing 4A, C myc promoter binding protein

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Galerie de données de validation

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  WB analysis using 26659-1-AP (same clone as 26659-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26659-1-AP (DENND4A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26659-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26659-1-PBS cible DENND4A dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DENND4A Protéine recombinante Ag24568
• Nom complet: DENN/MADD domain containing 4A
• Poids moléculaire observé: 230 kDa
• Numéro d’acquisition GenBank: BC041706
• Symbole du gène: DENND4A
• Identification du gène (NCBI): 10260
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DENND4A (DENN domain-containing protein 4A), also called IRLB and MYCPBP, is a probable guanine nucleotide exchange factor (GEF) that may activate RAB10. It can promote the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. It may bind to the ISRE-like element (interferon-stimulated response element) of the MYC P2 promoter (PMID: 20937701; 8056341).

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