Anticorps Recombinant de lapin anti-DHTKD1

DHTKD1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251575H1

N° de cat : 86661-3-PBS

Synonymes

2-oxoadipate dehydrogenase complex component E1, 2-oxoadipate dehydrogenase, mitochondrial, Alpha-KADH-E1, Alpha-ketoadipate dehydrogenase, Dehydrogenase E1 and transketolase domain-containing protein 1

---

Galerie de données de validation

• 

  WB analysis using 86661-3-RR (same clone as 86661-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86661-3-RR (DHTKD1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86661-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 86661-3-RR

  Biolayer interferometry (BLl) kinetic assays of 86661-3-RR against Human DHTKD1 were performed. The affinity constant is 1.99 nM.

---

Informations sur le produit

86661-3-PBS cible DHTKD1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: DHTKD1 Protéine recombinante Ag26515
• Nom complet: dehydrogenase E1 and transketolase domain containing 1
• Masse moléculaire calculée: 103 kDa
• Poids moléculaire observé: 103 kDa
• Numéro d’acquisition GenBank: BC007955
• Symbole du gène: DHTKD1
• Identification du gène (NCBI): 55526
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DHTKD1 (Dehydrogenase E1 And Transketolase Domain Containing 1), also named as 2-aminoadipic 2-oxoadipic aciduria protein, OADC-E1, OADH-E1, is a lesser-studied E1 enzyme among the family of 2-oxoacid dehydrogenases (PMID: 32695416). DHTKD1 was expressed ubiquitously in various tissues and was proposed to localize to the mitochondria (PMID: 23141294). DHTKD1 plays a critical role in energy production in mitochondria, suppression of DHTKD1 leads to impaired mitochondrial biogenesis and increased cell apoptosis (PMID: 24076469).

{{ptg:RelatedPrimaryAntibodies}}