Anticorps Polyclonal de lapin anti-DLGAP3

• Phare
• Validé par KD/KO

DLGAP3 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications(3)

N° de cat : 55056-1-AP

Synonymes

DAP 3, DAP3, DAP-3, Disks large-associated protein 3, PSD 95/SAP90 binding protein 3

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Galerie de données de validation

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  WB analysis using 55056-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 55056-1-AP (DLGAP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 55056-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55056-1-AP (DLGAP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules SH-SY5Y, tissu cérébral de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IF: See 1 publications below

Informations sur le produit

55056-1-AP cible DLGAP3 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: discs, large (Drosophila) homolog-associated protein 3
• Masse moléculaire calculée: 106 kDa
• Poids moléculaire observé: 106-120 kDa
• Numéro d’acquisition GenBank: NM_001080418
• Symbole du gène: DLGAP3
• Identification du gène (NCBI): 58512
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

DLGAP3, also named as DAP3, belongs to the SAPAP family. It may play a role in the molecular organization of synapses and neuronal cell signaling. DLGAP3 could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. It may induce enrichment of PSD-95/SAP90 at the plasma membrane. The antibody has no cross reaction to other DLGAP members.

Publications

Species	Application	Title
rat	WB	Biol Psychiatry; Metabotropic Glutamate Receptor and Fragile X Signaling in a Female Model of Escalated Aggression.; Authors - Laura E Been
mouse,human	WB,IF	Cell Death Dis; SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities.; Authors - Yanke Zhang ; KD Validated
mouse	WB	Nat Neurosci; Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding; Authors - Ezgi Hacisuleyman

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