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Anticorps Polyclonal de lapin anti-DLST

DLST Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31174-1-PBS

Synonymes

DLTS, OGDC E2

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using DLST Polyclonal antibody (31174-1-AP)

    WB analysis using 31174-1-AP (same clone as 31174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31174-1-AP (DLST antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31174-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using DLST Polyclonal antibody (31174-1-AP)

    IF Staining of HeLa using 31174-1-AP (same clone as 31174-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using DLST antibody (31174-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 31174-1-PBS in a different storage buffer formulation.

Informations sur le produit

31174-1-PBS cible DLST dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène DLST Protéine recombinante Ag34753
Nom complet dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Masse moléculaire calculée 49 kDa
Poids moléculaire observé40 kDa, 49 kDa
Numéro d’acquisition GenBankBC001922
Symbole du gène DLST
Identification du gène (NCBI) 1743
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DLST (Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex) ) is the E2 transferase of α-ketoglutarate dehydrogenase complex (KGDHC) that regulates the irreversible conversion of α-ketoglutarate to succinyl-CoA in the TCA cycle.RNAi knockdown of DLST led to decreased cell viability and induction of apoptosis in human T-ALL cell lines. High DLST expression predicts poor overall and recurrencefree survival among TNBC patients (PMID: 26876595, 34785772). DLST has two isoforms of 40 kDa, 49 kDa.

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