Anticorps Recombinant de lapin anti-DLX6

DLX6 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250408B4

N° de cat : 85946-1-PBS

Synonymes

Homeobox protein DLX-6

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Galerie de données de validation

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  WB analysis using 85946-1-RR (same clone as 85946-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85946-1-RR (DLX6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse embryo using 85946-1-RR (same clone as 85946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 85946-1-RR (DLX6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse embryo using 85946-1-RR (same clone as 85946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 85946-1-RR (DLX6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85946-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85946-1-RR against Human DLX6 were performed. The affinity constant is 5.65 nM.

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Informations sur le produit

85946-1-PBS cible DLX6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: DLX6 Protéine recombinante Ag19724
• Nom complet: distal-less homeobox 6
• Masse moléculaire calculée: 175 aa, 20 kDa
• Poids moléculaire observé: 32 kDa
• Numéro d’acquisition GenBank: BC069363
• Symbole du gène: DLX6
• Identification du gène (NCBI): 1750
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Distal-less homeobox 6 (DLX6) has been reported to play important roles in the development of craniofacial structures, inner ear, limb, and brain. DLX6 was significantly highly expressed in oral cancer tissues in The Cancer Genome Atlas database. DLX6 promotes cell proliferation and suppresses cell apoptosis in oral cancer cells. EGFR-CCND1 pathway might be the potential mechanism participating in the regulating axis (PMID: 33215805).

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