Anticorps Monoclonal anti-DMAP1

DMAP1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A4E8

N° de cat : 67183-1-PBS

Synonymes

DKFZp686L09142, DMAP1, DNMAP1, DNMT1 associated protein 1, DNMTAP1, EAF2, FLJ11543, KIAA1425, SWC4

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Galerie de données de validation

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  WB analysis using 67183-1-Ig (same clone as 67183-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67183-1-Ig (DMAP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67183-1-PBS in a different storage buffer formulation.

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  IF Staining of HEK-293 using 67183-1-Ig (same clone as 67183-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HEK-293 cells using DMAP1 antibody (67183-1-Ig, Clone: 1A4E8 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 67183-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67183-1-PBS cible DMAP1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: DMAP1 Protéine recombinante Ag28906
• Nom complet: DNA methyltransferase 1 associated protein 1
• Masse moléculaire calculée: 53 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC002855
• Symbole du gène: DMAP1
• Identification du gène (NCBI): 55929
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DMAP1 (DNA methyltransferase 1-associated protein 1) a component of the NuA4 histone acetyltransferase complex, was originally identified as an interacting molecule with DNA methyltransferase 1 (DNMT1) which co-localizes with PCNA at DNA replication foci. DMAP1 is required for DNA repair and acts against genomic instability. DMAP1 is widely implicated in transcription repression and activation via its interaction with multiple targets including histone deacetylase2 (HDAC2).

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