Anticorps Polyclonal de lapin anti-DMPK

DMPK Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16711-1-PBS

Synonymes

DMK, DM1PK, DM1 protein kinase, DM1, DM kinase

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Galerie de données de validation

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  WB analysis using 16711-1-AP (same clone as 16711-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16711-1-AP (DMPK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16711-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 16711-1-AP (same clone as 16711-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 16711-1-AP (DMPK antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16711-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 16711-1-AP (same clone as 16711-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 16711-1-AP (DMPK antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16711-1-PBS in a different storage buffer formulation.

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  IF Staining of U-251 using 16711-1-AP (same clone as 16711-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U-251 cells using DMPK antibody (16711-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 16711-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16711-1-PBS cible DMPK dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DMPK Protéine recombinante Ag10127
• Nom complet: dystrophia myotonica-protein kinase
• Masse moléculaire calculée: 629 aa, 69 kDa
• Poids moléculaire observé: 69-75 kDa
• Numéro d’acquisition GenBank: BC062553
• Symbole du gène: DMPK
• Identification du gène (NCBI): 1760
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DMPK (Myotonic Dystrophy Protein Kinase) is a serine-threonine protein kinase, strongly linked to myotonic dystrophy type 1 (DM1), the most prevalent muscular dystrophy in adults (PMID: 19309729). It is best known for its association with myotonic dystrophy type 1 (DM1), a multisystemic genetic disorder characterized by myotonia, muscle wasting, cardiac conduction defects, and other systemic manifestations (PMID: 24136222).

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