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Anticorps Polyclonal de lapin anti-DMRT1

DMRT1 Polyclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28149-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using DMRT1 Polyclonal antibody (28149-1-AP)

    WB analysis using 28149-1-AP (same clone as 28149-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28149-1-AP (DMRT1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28149-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse testis tissue using DMRT1 Polyclonal antibody (28149-1-AP)

    IF Staining of mouse testis using 28149-1-AP (same clone as 28149-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using DMRT1 antibody (28149-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28149-1-PBS in a different storage buffer formulation.

Informations sur le produit

28149-1-PBS cible DMRT1 dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène DMRT1 Protéine recombinante Ag28006
Nom complet doublesex and mab-3 related transcription factor 1
Masse moléculaire calculée 39 kDa
Poids moléculaire observé39 kDa
Numéro d’acquisition GenBankBC040847
Symbole du gène DMRT1
Identification du gène (NCBI) 1761
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DMRT1, also named DMT1, belongs to the DMRT family. DMRT1 is one of the most conserved transcription factors in a variety of species and is involved in sex determination and germ cell differentiation. DMRT1 prevents the sexual switch from male to female, represses pluripotency, and balances mitosis versus meiosis. DMRT1 also maintains spermatogenesis and replenishes mGSCs by collaborating with Plzf and Sal-like protein 4 (PMID: 33420764). DMRT1 has 3 isoforms with the molecular mass of 18, 29, and 39 kDa.

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