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Anticorps Polyclonal de lapin anti-DNAJC17

DNAJC17 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31580-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using DNAJC17 Polyclonal antibody (31580-1-AP)

    WB analysis using 31580-1-AP (same clone as 31580-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31580-1-AP (DNAJC17 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31580-1-PBS in a different storage buffer formulation.

Informations sur le produit

31580-1-PBS cible DNAJC17 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène DNAJC17 Protéine recombinante Ag35992
Nom complet DnaJ (Hsp40) homolog, subfamily C, member 17
Masse moléculaire calculée 304 aa, 35 kDa
Poids moléculaire observé 34 kDa
Numéro d’acquisition GenBankBC000048
Symbole du gène DNAJC17
Identification du gène (NCBI) 55192
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

DnaJ proteins, also known as Hsp40, are a set of highly conserved proteins typically acting as co-factors of Hsp70 molecular chaperones. Based on their domain architecture, DNAJ is classified into three different groups (A, B, and C). DNAJC17 belongs to group C, bearing the J domain at its N-terminal region and an RNA recognition motif (RRM) located at the protein C-terminu. DNAJC17 is a susceptibility gene for congenital hypothyroidism and demonstrated its wide expression in mice since early embryogenesis, in which it plays an essential role in pre-implantation stages (PMID: 29773831).

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